Altered dynamics of neurovascular coupling in CADASIL.

This analysis confirmed a difference in functional hyperemia dynamics that remained highly significant in response to 40‐sec stimulations (visual, P = 1.28 × 10 −5 ; motor, P = 1.18 × 10 −6 ), but not to 20‐sec stimulations (visual, P = 0.133; motor, P = 0.431).

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Although there was a trend toward diminished functional hyperemia in patients compared with control subjects over 20‐sec stimulation blocks, these differences did not reach statistical significance (visual, P = 0.151; motor, P = 0.181).

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