An increased SNP rate was not necessarily expected, since Pf WRN is reported to lack the proofreading exonuclease domain found in human WRN [ 22 ], and importantly the SNP datasets were all very small, making changes in SNP rate only marginally significant.
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RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics.
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