Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.

121 A meta-analysis of eight RCTs (38 153 patients on statin therapy), showed a trend between attained LDL-C level and risk for haemorrhagic stroke, although the absolute number of haemorrhagic strokes was low. 122 A subsequent meta-analysis including 248 391 patients, however, found no significant increased risk of intracerebral haemorrhage based on data from RCTs (RR 1.10, 95% CI

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