mTORC1 Activation by Loss of <i>Tsc1</i> in Myelinating Glia Causes Downregulation of Quaking and Neurofascin 155 Leading to Paranodal Domain Disorganization.

Front Cell Neurosci · 2018 · PMC6052123 · PMID 30050412

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highly significantno p-value reported

Even though the effectiveness of rescue upon Rapamycin treatment in mutant animal is highly significant, the control littermates receiving rapamycin showed no significant changes compared to non-Rapamycin treated controls.

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showed a trendno p-value reported

Furthermore the mutant axons showed a trend towards increased diameter when compared to control, as quantified in Figure 3E .

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