The VSG in their study caused a significant ∼20–25% decrease in glucose AUC in their Glp1r WT group compared with sham-operated controls, while surgery reduced the sham-adjusted glucose AUC by only ∼15% in their Glp1r β-cell-ko mice, a change that did not reach statistical significance.
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Enhanced Glucose Control Following Vertical Sleeve Gastrectomy Does Not Require a β-Cell Glucagon-Like Peptide 1 Receptor.
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