Identification of Human B-1 Helper T Cells With a Th1-Like Memory Phenotype and High Integrin CD49d Expression.

Front Immunol · 2018 · PMC6054961 · PMID 30061889

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When we compared expression levels of these gene between CXCR5 − CD49d high CD4 + T cells and CXCR5 + CD4 + Tfh cells, CXCR5 − CD49d high CD4 + T cells showed a trend of higher expression of TBX21, EOMES, CXCR3, and PRDM1 and lower expression of IL-21, BCL-6 , and CXCR5 than Tfh cells, except BCL6 in the circulating Tfh cells ( 20 ) (Figure S3 in Supplementary Material).

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