At similar weight loss, dietary composition determines the degree of glycemic improvement in diet-induced obese C57BL/6 mice.

Whereas the hepatic TG content in R-NC mice (27.6 ± 4.3 mg TG/g liver) was also lower than in OBESE mice (P 0.0092), the TG content in livers of R-HF mice was in between that of the LEAN and OBESE mice, but the difference did not reach statistical significance (P 0.4219 vs OBESE and P 0.1328 vs LEAN) ( Fig 4c ).

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