Moreover, while mice that received (+)-SW209415 continuously had a nearly 4-fold increase in bone marrow SKL cells (from 3707 to 14007, P =0.0026), mice that received only 7 days of (+)-SW209415 had only a 1.54-fold increase that did not reach statistical significance ( Online Supplementary Figure S7 ).
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A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support.
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