<i>Ex vivo</i> anti-inflammatory effects of probiotics for periodontal health.

paracasei LPc-G110 toothpaste (100 mg) induced statistically significant dose-dependent reductions in the LPS-stimulated release of three (IL-6, IL-8 and PGE 2 ) of the six inflammatory mediators, compared to the placebo control (100 mg), when administered at concentrations ranging from 0.5% to 10% ( Figure 8(c , d, e)); a reduction in 8-isoprostane was also indicated but did not reach statistical significance ( Figure 8(f )).

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