The associations between serum adiponectin, leptin, C-reactive protein, insulin, and serum long-chain omega-3 fatty acids in Labrador Retrievers.

1 , 2 , 34 The implications on other diseases such as diabetes and cancer are currently unknown, but it is suspected that contributions may be significant for dogs. 34 , 35 For example, orthopedic diseases show a strong correlation with obesity status in dogs, and weight loss can significantly improve orthopedic function. 36 It has been suggested that obesity-associated inflammation contributes to the development and progression of osteoarthritis, an

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25 , 26 In dogs, CRP and obesity, much like adiponectin, does not have a clear trend in obesity with some studies showing increased CRP in obese populations, or decreases after weight loss, while others show no changes with obesity status. 4 , 7 , 9 , 27 These discrepancies in the canine literature suggest that there may be other confounding factors that affect these adipokines.

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