The responses to the conserved IpaH followed the same pattern as those described above against IpaA; signal increases were detected post-CVD 1204 vaccination, particularly in the highest-dose group, and post-Sf2a challenge (although they did not reach statistical significance for any disease outcome and were blunted in the severe-disease group) ( Fig. 3B , bottom).
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A Novel <i>Shigella</i> Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge.
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