The risk of LC was calculated among the following rankings of risk severe asthma without regular ICS use, low severity without regular ICS, high severity with regular ICS, and low severity with regular ICS group showed a decreasing trend of LC incidence ( P = 0.041).
heral lung nodules decreased in size after treatment.[ 23 ] Similarly, a clinical trial of fluticasone for 6 months in patients with squamous dysplasia showed that more patients showed a decrease and fewer an increase in the number of nodules detected on chest CT in the treatment arm, although this failed to reach statistical significance.[ 24 ] It is reported that budesonide was quite effective in protecting against pulmonary carcinogenicity caused by cigarette smoke.[ 25 ] Against that, treatment with inhaled budesonide for 1 year in smokers did not significantly affect the size of CT-detected peripheral lung nodules in a randomiz