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Implementation of environmental enrichment after middle age promotes healthy aging.

Aging (Albany NY) · 2018 · PMC6075449 · PMID 30036185

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showed a trendno p-value reported
EE initiated at 18-month of age significantly improved glycemic control and showed a trend of positive impact on mean lifespan.

also in 53,322 other papers

an increasing trendno p-value reported
Leptin expression was reduced by over 80% while adiponectin expression showed an increasing trend.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.