Transgenic rats of both lines showed a trend towards hind limb clasping at 2 months of age as indicated by their higher scores and they reached significant levels at 11 months of age in both lines [line 4 ( P <0.01) and line 8 ( P <0.05)] when compared to non-transgenic controls.
← all excerpts
Dynamic nuclear envelope phenotype in rats overexpressing mutated human torsinA protein.
1
—
—