Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.

Nat Biotechnol · 2018 · PMC6078800 · PMID 30010674

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did not reach statistical significanceno p-value reported

12 ) and only a small effect on MDSCs, which did not reach statistical significance ( Supplementary Fig. 13 ).

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