Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.

Nat Commun · 2018 · PMC6079028 · PMID 30082721

Europe PMC DOI

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nominally significantP = 6.87 × 10 −10actually significant

Although the observed sign concordance of 52% is not significantly different from a random pattern ( P = 0.40), we find 3.23 times more SNPs in this set of 506 SNPs that are nominally significant for SZ than expected given the distribution of the P values in the SZ GWAS results (raw enrichment P = 6.87 × 10 −10 ).

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