Differences in clinical features between optic neuritis in neuromyelitis optica spectrum disorders and in multiple sclerosis.

33 showed a trend toward more posterior involvement of the optic nerve in the NMO group with chiasmatic enhancement seen in NMO patients, but this was not significant, while Ramanathan and colleagues 14 reported that the majority of anti-AQP4-positive ON patients had involvement of the intracranial portion of the optic nerve and exhibited longitudinally extensive ON.

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