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<i>NLRP3</i> expression in mesencephalic neurons and characterization of a rare <i>NLRP3</i> polymorphism associated with decreased risk of Parkinson's disease.

NPJ Parkinsons Dis · 2018 · PMC6093937 · PMID 30131971

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Although the direction of effect reported in PDgene is consistent with our results, it did not reach statistical significance, potentially due to reduced imputation accuracy for rare variants.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.