Barely Significant
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Correlation of Serum Biomarkers and Magnetic Resonance Spectroscopy in Monitoring Disease Progression in Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Due to mtDNA A3243G Mutation.

Front Neurol · 2018 · PMC6094978 · PMID 30140253

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a negative trendno p-value reported
a positive trendno p-value reported
In addition, although the results were not statistically significant, we observed that the correlation between the serum lactate and the MRS lactate peak changed from a positive to a negative trend when compared to the acute stage, when the correlation between the serum Lac/Pyr ratio and the severity of the MRS lactate peak continued to show a positive trend.

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