Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

PLoS One · 2018 · PMC6095522 · PMID 30114225

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0.0001

closest p · 0.0× alpha

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The sentences

marginally significantp-value = 1E-4actually significant

E2 treatment when compared to DHT treatment in ovariectomized females resulted in activation of Nrf2 that was marginally significant (p-value = 1E-4) (Lane 1).

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did not reach statistical significancep-value > 1E-2actually significant

Ovariectomy compared to intact mice from two biosets had no effect on Nrf2 activation, and two biosets from castrated mice exhibited Nrf2 activation, but these comparisons did not reach statistical significance (p-value > 1E-2) (data not shown).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.