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Enhanced autophagy contributes to protective effects of IL-22 against acetaminophen-induced liver injury.

Theranostics · 2018 · PMC6096391 · PMID 30128045

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The up-regulation of LC3-II by IL-22 administration in APAP-treated L02 cells failed to reach statistical significance, suggesting there is the possible involvement of other cells in IL-22-induced up-regulation of autophagy in the hepatocytes of APAP-treated mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.