Whereas for the collagens there was reduced mRNA expression in the mice treated with antagomir-199b but this effect did not reach statistical significance, we did observe significant reduction in fibronectin1 expression in the mice treated with antagomir-199b compared to the control group ( Fig. 3 h).
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miR-199b-5p is a regulator of left ventricular remodeling following myocardial infarction.
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