Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews.

Indian Heart J · 2018 · PMC6097169 · PMID 30122240

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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showed a trendp < 0.00001actually significant

For resting EF (384 patients), the weighted mean difference showed a trend of 1.9% in favor of CoQ10 (95% CI −0.13 to +3.9). 4 Upon meta-analysis, there was a 3.7% net improvement in EF (1.59 to 5.77; p < 0.00001). 35 3.4.

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a positive trendno p-value reported

33 In addition, three of the meta-analyses showed a positive trend towards an improvement in ejection fraction and cardiac outputs.

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