An increasing trend in TDR was specifically observed in mutations to non-nucleoside reverse transcriptase inhibitors (NNRTIs).
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Prevalence and Transmission Dynamics of HIV-1 Transmitted Drug Resistance in a Southeastern Cohort.
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The sentences
The prevalence of TDR over time varied by drug class; NNRTI-associated SDRMs increased across the study period ( P < .01), whereas NRTI and PI resistance did not show a significant trend ( Figure 1B ).