Injection of mRNAs encoding for this mutant form triggered quite significant decrease of CD41:eGFP+ hematopoietic cells in the CHT at 48hpf (in addition to small haemorrhaging within the brain and, apparently, the pericardial space, which appears to be consistent with the phenotype obtained with Runx1 deficient mouse embryos (Okuda et al., 1996; Wang et al., 1996)).
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Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish.
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