Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice.

TNFα expression was significantly decreased after Andro-S treatment compared with the model group; IL6 expression also trended slightly lower, although this decrease did not reach statistical significance (Figure 2 ). iTRAQ-based proteomics identification of differentially expressed proteins in lung tissue sections from different treatment group To elucidate the probable mechanism of Andro-S effects on pulmonary inflammation, we designed four independent 8-plex iTRAQ experiments on lung tissue sections from five different groups: blank group, control group, model group, low-dose treatment group, and high-dose treatment group.

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