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Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma.

Invest Ophthalmol Vis Sci · 2017 · PMC6108236 · PMID 28384726

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At 6 weeks after transplantation, iPSC-TM recipients exhibited a reduction of IOP and slight improvement of outflow facility when compared to values in PBS recipients, but these data did not reach statistical significance (13.75 ± 2.27 mm Hg vs. 16.75 ± 4.22 mm Hg; 0.0087 ± 0.0045 μl/min/mm Hg vs. 0.0066 ± 0.0033 μl/min/mm Hg).

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