Survival outcomes according to tumor stage confirmed significant differences between the two groups of GSN expression ( p = 0.021 for stage II patients; p = 0.027 for stage III patients), and showed a trend toward better survival rates in the OAS2 overexpression group than in the underexpression group.
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Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively.
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