Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels.

The G×G is genome-wide significant for tau , has a nominally significant interaction for Aβ42 ( p = 0.0013), and the pattern of interaction differs for the two traits in a way that creates the rQTL pattern of tau / Aβ42 correlation changes across genotypes (see Fig. 1a ).

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