Better approach for autoimmune pulmonary alveolar proteinosis treatment: inhaled or subcutaneous granulocyte-macrophage colony-stimulating factor: a meta-analyses.

In 2012, one meta-analyses reported that inhaled GM-CSF therapy showed a trend toward higher response rate in aPAP patients comparing with subcutaneous route, suggesting inhaled route might be a better route for GM-CSF therapy [ 34 ].

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