Metabolomic analysis of obesity, metabolic syndrome, and type 2 diabetes: amino acid and acylcarnitine levels change along a spectrum of metabolic wellness.

Our data revealed that lysine increased with metabolic unwellness ( p = 0.0006), a previously unreported finding, and had nearly significant increases in obese and diabetic states ( p = 0.009 and p = 0.008, respectively) ( Table 2 , Fig. 1 ).

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