Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase-1 Inhibitors with Decreased P-Glycoprotein Interactions.

ACS Omega · 2018 · PMC6120739 · PMID 30198004

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

These in silico studies indicated a clear trend between the binding profiles of the selected compounds, and the distance between the methoxy oxygen atom of the ligand and the ARG878 residue in the PARP-1 binding pocket ( Table 2 ).

also in 13,370 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.