The CSPG4 CAR-transfected NKT cells showed a trend towards higher cytotoxicity compared with the CD8 + CAR-T cells, without reaching statistical significance ( Figure 4 and Table S8 ).
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The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma.
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The statistical investigation concerning the antigen-specificity of lysis revealed a highly significant increase in the cytolytic capacity of both of the cell populations after co-cultivation with the A375M cells compared with stimulation with the T2.A1 cells for all effector-to-target ratios ( Table S9 ).