Intracellular inflammatory and antioxidant pathways in postmortem frontal cortex of subjects with major depression: effect of antidepressants.

When considering the ratio between the phosphorylated and the total forms of the proteins, the increase for p-ERK1/2/total ERK1/2 did not reach statistical significance whereas p-JNK/total JNK and p-p38/total p38 were clearly higher in MDD than in controls (Fig. 2e ).

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