Duration of physical activity, sitting, sleep and the risk of total knee replacement among Chinese in Singapore, the Singapore Chinese Health Study.

When we summated the duration on all three types of physical activity for each participant, compared to spending less than 0.5 hours/week on physical activity, spending 5 or more hours/week was associated with increased risk of TKR (HR 1.10, 95% CI 0.96–1.26), while spending intermediate duration of 0.5-<2 hours/week was associated with reduced risk (HR 0.88, 95% CI 0.73–1.05), However, we noted that both risk estimates did not reach statistical significance in the fully adjusted model (Model 3) ( Table 2 ).

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