Barely Significant
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Does Melatonin and Melatonin Agonists Improve the Metabolic Side Effects of Atypical Antipsychotics?: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Clin Psychopharmacol Neurosci · 2018 · PMC6124875 · PMID 30121990

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nearly significantno p-value reported
At week eight, melatonin was associated with significantly less weight gain (mean difference [MD] 3.2 kg, p =0.023), increase in waist circumference (MD 2.83 cm, p =0.041) and TG concentration (MD 62 mg/dl, p =0.090 [nearly significant]) than the placebo.

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