Barely Significant
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Typhoid Fever in Chile 1969-2012: Analysis of an Epidemic and Its Control.

Am J Trop Med Hyg · 2018 · PMC6128366 · PMID 30047371

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a negative trendno p-value reported
The pre-epidemic period is the starting point of the series; TF IR was higher at the beginning of this segment than at the beginning of the next, with a negative trend in the entire pre-epidemic period.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.