Barely Significant
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Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study.

BMC Anesthesiol · 2018 · PMC6128996 · PMID 30193588

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The sentences

a clear trendno p-value reported
Also, we did not observe a clear trend in propofol dose over time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.