a statistical trendp value = 0.09
A_prom CpG1 showed a statistical trend to be highly methylated in AD cases compared to controls [23 ± 7.8% vs. 18.4 ± 6.2%; p value = 0.09] and a statistically significant difference in DNA methylation levels was observed for A_prom CpG2 in AD cases compared to controls [21.5 ± 5.8% vs. 15.3 ± 3.8%; p value < 0.01].