Bourgeois et al 22 reported a significant trend of increased ADE-related visits to outpatient clinics in the United States, from 9.1 to 16.9 visits per 1000 persons between 1995 and 2005. 22 Emergency department visits have not been evaluated, because of low incidence.
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Analysis of Drug-Drug Interactions in Swiss Claims Data Using Tizanidine and Ciprofloxacin as a Prototypical Contraindicated Combination.
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