Barely Significant
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Effect of interferon beta-1a subcutaneously three times weekly on clinical and radiological measures and no evidence of disease activity status in patients with relapsing-remitting multiple sclerosis at year 1.

BMC Neurol · 2018 · PMC6137887 · PMID 30217172

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Although there was a consistent trend for estimates of relative treatment effects in favor of IFN β-1a 44 μg SC tiw compared with placebo across all other patient subgroups, it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.