What have we learned from observational studies and clinical trials of mild to moderate COPD?

Respir Res · 2018 · PMC6142698 · PMID 30223834

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showed a trendno p-value reported

In a PC setting, GOLD I and II patients also showed a trend to improving trough FEV1 with tiotropium compared with placebo after 12 weeks [effect size 40 ml (95%CI -30, 100)] [ 62 ].

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