High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults.

Front Immunol · 2018 · PMC6143653 · PMID 30258437

Europe PMC DOI

hedged sentences

0.1700

closest p · 3.4× alpha

0.1700

boldest claim

The sentences

did not reach statistical significancep = 0.17not close (p > 0.1)

0.3%) in infected children compared to adults, although this did not reach statistical significance ( p = 0.17; Figure 5B ).

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a positive trendno p-value reported

This is corroborated by a positive trend between the frequency of circulating T FR and neutralization breadth in HIV infected children and negative trend in the same group between PD1 expression and breadth (Figures S3F,G).

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