highly significantp = 0.0001
The difference between the microbiome profiles of these groups was highly significant ( p = 0.0001, F = 13.75) ( Fig 5B ).
The difference between the microbiome profiles of these groups was highly significant ( p = 0.0001, F = 13.75) ( Fig 5B ).
Although microbiomes from individuals with active disease (DAS28 score ≥2.6) had lower Shannon Diversity index p = 0.024, Mann-Whitney test) than the microbiomes from individuals in remission (DAS28 score <2.6) ( Fig 3A ), the difference in microbiome profiles between the two groups did not reach statistical significance ( p = 0.07, PERMANOVA).