The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma.

Pharmacogenomics J · 2018 · PMC6150906 · PMID 29298996

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nominally significantno p-value reported

Four nominally significant trans-eQTLs were predicted to regulate three candidate genes ( SELL , MTF2 , and GAL ), the expression of which was significantly reduced in LCLs following zileuton treatment.

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