Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives.

Molecules · 2017 · PMC6155269 · PMID 28335499

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closest p

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quite significantno p-value reported

This regioselectivity can be the result of steric interactions between the N -substituent of the pyrrole and the cyclic imine which can be quite significant due to the bulkiness of the trifluoromethyl group and its specific nature and, the C3 isomers were formed.

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