Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging.

Aging Cell · 2018 · PMC6156495 · PMID 30129215

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did not reach statistical significanceno p-value reported

The mRNA levels of these genes were elevated in Sox2‐TK mice after GCV treatment, although in the case of Ink4a the increase did not reach statistical significance (Figure 1 h), corroborating the induction of senescence in Sox2‐TK tissues.

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