In two Phase I studies, low doses of noribogaine (the active metabolite of ibogaine, which has a distinct pharmacological profile) was well tolerated ( Glue et al., 2015 ) and showed a trend toward reduction in opioid withdrawal ratings ( Glue et al., 2016 ).
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Subjective effectiveness of ibogaine treatment for problematic opioid consumption: Short- and long-term outcomes and current psychological functioning.
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