INFERNO: inferring the molecular mechanisms of noncoding genetic variants.

For lower-powered GWAS datasets or those with sparse association signals, INFERNO uses GWAS summary statistics to identify all significant or almost significant variants within a user-defined window around each tagging variant ( p -value expansion).

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For lower-powered GWAS data, the p -value expansion enables the analysis of nominally significant signals near genome-wide significant signals by taking the full GWAS summary statistics as well as LD structure into account, potentially capturing causal variants underlying association signals.

also in 7,732 other papers