DNA Mismatch Repair Protein Immunohistochemistry and MLH1 Promotor Methylation Testing for Practical Molecular Classification and the Prediction of Prognosis in Endometrial Cancer.

Cancers (Basel) · 2018 · PMC6162750 · PMID 30134578

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0570

boldest claim

The sentences

borderline significancep = 0.051so close (0.05 < p ≤ 0.1)

MMR deficiency was associated with postmenopausal status, tumor grades 2–3, FIGO stages I–II ( p = 0.010, 0.011, 0.006), BMI < 25, and parous state (parity ≥ 1) with borderline significance ( p = 0.051, 0.064).

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showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

Prognosis Cases with MMR deficiency showed a trend of poor progression-free survival (PFS) and overall survival (OS) ( p = 0.057, 0.076) ( Figure 3 A,B).

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a trend toward significanceno p-value reported

All analyses were conducted using SPSS version 23.0 (IBM, Armonk, NY, USA) and R software, version 3.2.5 for Windows (the R foundation for statistical computing, Vienna, Austria), and p -values < 0.05 were considered statistically significant; p -values between 0.05 and 0.15 were considered as a trend toward significance. 5.

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